School of Biomedical Sciences

Wilson, CP, Ward, M, McNulty, H, STRAIN, JJ, Trouton, TG, Horigan, G, Purvis , J and Scott, JM (2012) Riboflavin offers a targeted strategy for managing hypertension in patients with the MTHFR 677TT genotype: a 4-y follow-up. American Journal of Clinical Nutrition, 95 (3). pp. 766.

Tighe, Paula, Ward, Mary, McNulty, Helene, Finnegan, Owen, Dunne, Adrian, Strain, Sean, Molloy, Anne M, Duffy, Maresa, Pentieva, Kristina and Scott, John M (2011) A dose-finding trial of the effect of long-term folic acid intervention: implications for food fortification policy.. American Journal of Clinical Nutrition, 93. pp. 11-18.

McNulty , B, Pentieva, K, Marshall , B, Ward, Mary, Molloy , AM, Scott, JM and McNulty, H (2011) Women's compliance with current folic acid recommendations and achievement of optimal vitamin status for preventing neural tube defects.. Human Reproduction, 26 (6). pp. 1530-1536.

Wallace, JMW, McCormack, JM, McNulty, H, Walsh, PM, Robson, PJ, Bonham, MP, Duffy, ME, Ward, M, Molloy, AM, Scott, JM, Ueland, PM and Strain, JJ (2011) Choline supplementation and measures of choline and betaine status: a randomised, controlled trial in postmenopausal women. British Journal of Nutrition. pp. 1.

Price, Ruth K., Keaveney, Edel M, Hamill, Lesley L, Wallace, Julie, Ward, Mary, Ueland, Per M, McNulty, Helene, Strain, JJ, Parker, MJ and Welch, RW (2010) Consumption of wheat aleurone-rich foods increases fasting plasma betaine and modestly decreases fasting homocysteine and LDL-cholesterol in adults. Journal of Nutrition, 140. pp. 2153-2157.

Horigan, G, McNulty, H, Ward, M, Strain, J.J., Purvis, J and Scott, J.M. (2010) Riboflavin lowers blood pressure in cardiovascular disease patients homozygous for the 677C-->T polymorphism in MTHFR.. Journal of Hypertension, 28. pp. 478-486.

Wilson, Carol, McNulty, Helene, Scott, JM, Strain, JJ and Ward, Mary (2009) The MTHFR C677T polymorphism, B-vitamins and blood pressure.. Proceeding of the Nutrition Society, 69.

McNulty, Helene and Pentieva, Kristina (2009) Folate bioavailability. In: Folate in Health and Disease. CRC Press, pp. 25-48. ISBN 978-1420071245

Hammons, Andrea L, Summers, Carolyn M, Woodside, Jayne V, McNulty, Helene, Strain, J.J, Young, Ian S, Murray, Liam, Boreham, Colin A, Scott, John M, Mitchell, Laura E and Whitehead, Alexander S (2009) Folate/homocysteine phenotypes and MTHFR 677C > T genotypes are associated with serum levels of monocyte chemoattractant protein-1. CLINICAL IMMUNOLOGY, 133 (1). pp. 132-137.

Stanislawska-Sachadyn, Anna, Mitchell, Laura E., Woodside, Jayne V., Buckley, Peter T., Kealey, Carmel, Young, Ian S., Scott, John M., Murray, Liam, Boreham, Colin A., McNulty, Helene, Strain, J.J. and Whitehead, Alexander S. (2009) The Reduced Folate Carrier (SLC19A1) c.80G > A Polymorphism is Associated with Red Cell Folate Concentrations Among Women. ANNALS OF HUMAN GENETICS, 73 (Part 5). pp. 484-491.

Hoey, Leane, McNulty, H and Strain, JJ (2009) Studies of biomarker responses to intervention with riboflavin: a systematic review. AMERICAN JOURNAL OF CLINICAL NUTRITION, 89 (6). pp. 1960S-1980S.

Hoey, Leane, Strain, JJ and McNulty, Helene (2009) Studies of biomarker responses to intervention with vitamin B-12: a systematic review of randomized controlled trials. American Journal of Clinical Nutrition, 89 (6). pp. 1981S-1996S.

Kerr, Maeve, Livingstone, Barbara, Bates, Christopher J., Bradbury, Ian, Scott, John M., Ward, Mary, Pentieva, Kristina, Mansoor, Mohammad Azam and McNulty, Helene (2009) Folate, Related B Vitamins, and Homocysteine in Childhood and Adolescence: Potential Implications for Disease Risk in Later Life. PEDIATRICS, 123 (2). pp. 627-635.

Hoey, Leane, McNulty, Helene, McCann, Elizabeth M. E, McCracken, Kelvin J, Scott, John M, Marc, Barbara Blaznik, Molloy, Anne M, Graham, C and Pentieva, Kristina (2009) Laying hens can convert high doses of folic acid added to the feed into natural folates in eggs providing a novel source of food folate. BRITISH JOURNAL OF NUTRITION, 101 (2). pp. 206-212.

Whittle, C.R., Ward, M, Strain, J.J. and McNulty, H (2009) Hyperhomocysteinemia, B vitamins and bone health.. Osteoporosis Review, 17 (4). pp. 18-21.

Rea, I. Maeve, Myint, Phyo K., Mueller, Heiko, Murphy, Anne, Archbold, G. Pooler R., McNulty, H. and Patterson, Chris C. (2009) Nature or nurture; BMI and blood pressure at 90. Findings from the Belfast Elderly Longitudinal Free-living Aging STudy (BELFAST). AGE, 31 (4). pp. 261.

Bekaert, Bram, Cooper, Matthew L., Green, Fiona R., McNulty, Helene, Pentieva, Kristina, Scott, John M., Molloy, Anne M. and Rayman, Margaret P. (2008) Effect of selenium status and supplementation with high-selenium yeast on plasma homocysteine and B vitamin concentrations in the UK elderly. MOLECULAR NUTRITION & FOOD RESEARCH, 52 (11). pp. 1324-1333.

McNulty, Helene and Scott, John M. (2008) Intake and status of folate and related B-vitamins: considerations and challenges in achieving optimal status. BRITISH JOURNAL OF NUTRITION, 99 (Suppl. 3). pp. S48-S54.

McNulty, H, Pentieva, Kristina, Hoey, Leane and Ward, Mary (2008) Homocysteine, B-vitamins and CVD. PROCEEDINGS OF THE NUTRITION SOCIETY, 67. pp. 232-237.

Wallace, Julie, Bonham, Maxine P, Strain, Sean, Duffy, E. M, Robson, Paula J, Ward, Mary, McNulty, Helene, Davidson, Philip W, Myers, Gary J, Shamlaye, Conrad F, Clarkson, Tom W, Molloy, Anne M, Scott, John M and Ueland, Per M (2008) Homocysteine concentration, related B vitamins, and betaine in pregnant women recruited to the Seychelles Child Development Study. AMERICAN JOURNAL OF CLINICAL NUTRITION, 87 (2). pp. 391-397.

Williams, Emma, Stewart-Knox, Barbara, McConville, Christopher, Bradbury, Ian, Armstrong, Nicola C. and McNulty, Helene (2008) Folate status and mood: is there a relationship?. PUBLIC HEALTH NUTRITION, 11 (2). pp. 118-123.

Dickey, William, Ward, M., Whittle, Claire R, Kelly, Mary T, Pentieva, Kristina, Horigan, Geraldine, Patton, Sharon and McNulty, H (2008) Homocysteine and related B-vitamin status in coeliac disease: Effects of gluten exclusion and histological recovery. Scandinavian Journal of Gastroenterology, 43 (6). pp. 682-688.

Dickey, William, Ward, Mary, Whittle, Claire R., Kelly, Mary T., Pentieva, Kristina, Horigan, Geraldine, Patton, Sharon and McNulty, Helene (2008) Homocysteine and related B-vitamin status in coeliac disease: Effects of gluten exclusion and histological recovery. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 43 (6). pp. 682-688.

Stanisławska-Sachadyn, Anna, Brown, Karen S., Mitchell, Laura E., Woodside, Jayne V., Young, Ian S., Scott, John M., Murray, Liam, Boreham, Colin A., McNulty, H., STRAIN, JJ and Whitehead, Alexander S. (2008) An insertion/deletion polymorphism of the dihydrofolate reductase (DHFR) gene is associated with serum and red blood cell folate concentrations in women. Human Genetics, 123 (3). pp. 289.

Wallace, Julie, Bonham, M. P., Duffy, E. M., Robson, P. J., Ward, Mary, McNulty, Helene, Davidson, P. W., Myers, G. J., Clarkson, T. W., Shamlaye, C. F., Molloy, A. M., Scott, J. M. and Strain, Sean (2007) Homocysteine and related B-vitamin concentration in pregnant women recruited as part of the Seychelles Child Development Study. PROCEEDINGS OF THE NUTRITION SOCIETY, 66 (Sp. Iss. SI). pp. 65A.

Horigan, Geraldine, Ward, M., McNulty, Helene, Purvis, J., Strain, Sean and Scott, J. M. (2007) Riboflavin lowers blood pressure in patients with premature CVD homozygous for the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism. PROCEEDINGS OF THE NUTRITION SOCIETY, 66 (Sp. Iss. SI). pp. 95A.

Bekaert, B., Cooper, M. L, Green, F, McNulty, H, Pentieva, Kristina, Scott, J, Molloy, A and Rayman, M. P (2007) Selenium status influences the effect of folate, vitamin B12 and pyridoxal 5 `-phosphate on homocysteine concentrations. PROCEEDINGS OF THE NUTRITION SOCIETY, 66 (Sp. Iss. SI). pp. 36A.

Gallagher, Alison, Neville, C. E., Murray, L. J., Strain, Sean, Boreham, C. A. G., Young, I. and McNulty, Helene (2007) Is there a relationship between B-vitamin status and bone mineral density in young adults? Evidence from the Young Hearts Project, Northern Ireland. PROCEEDINGS OF THE NUTRITION SOCIETY, 66 (Sp. Iss. SI). pp. 104A.

Whittle, C. R., Strain, JJ, Ward, M, Molloy, A. M., Scott, J. M., McCandless, A. S. and McNulty, H (2007) Is the C677T methylenetetrahydrofolate reductase (MTHFR) polymorphism a risk factor for osteoporosis? A pilot study. PROCEEDINGS OF THE NUTRITION SOCIETY, 66 (Sp. Iss. SI). pp. 33A.

McNulty, B., Pentieva, Kristina, Marshall, B., Ward, Mary, Molloy, A. M., Scott, J. M. and McNulty, H. (2007) Folate status in pregnant women in relation to compliance with current folic acid recommendations for the prevention of neural-tube defects. PROCEEDINGS OF THE NUTRITION SOCIETY, 66 (Sp. Iss. SI). pp. 65A.

Wasson, Gillian R, McGlynn, Angela P, McNulty, Helene, O'Reilly, Sharleen L, McKelvey-Martin, Valerie, McKerr, George, Strain, JJ, Scott, John and Downes, Stephen (2006) Global DNA and p53 region-specific hypomethylation in human colonic cells is induced by folate depletion and reversed by folate supplementation. JOURNAL OF NUTRITION, 136 (11). pp. 2748-2753.

McKillop, Derek J., McNulty, Helene, Scott, John M., McPartlin, Joseph M., Strain, JJ, Bradbury, Ian, Girvan, Jayne, Hoey, Leane, McCreedy, Richard, Alexander, Joy, Patterson, B. Karen, Hannon-Fletcher, Mary P.A and Pentieva, Kristina (2006) The rate of intestinal absorption of natural food folates is not related to the extent of folate conjugations. AMERICAN JOURNAL OF CLINICAL NUTRITION, 84 (1). pp. 167-173.

McNulty, Helene, Dowey, Le Roy, Strain, Sean, Dunne, A, Ward, M, Molloy, A, McAnena, LB, Hughes, JP, Hannon-Fletcher, Mary PA and Scott, John (2006) Riboflavin lowers homocysteine in individuals homozygous for the MTHFR 677C->T polymorphism.. Circulation, 113 (1). pp. 74-80.

Williams, E, Stewart-Knox, Barbara J., Bradbury, I, Rowland, I, Pentieva, Kristina, Helander, A and McNulty, H (2005) Effect of folic acid supplementation on mood and serotonin response in healthy males. British Journal of Nutrition, 94 (4). pp. 602-608.

Holmes, VA, Wallace, Julie, Alexander, HD, Gilmore, WS, Bradbury, I, Ward, Mary, Scott, JM, McFaul, P and McNulty, Helene (2005) Homocysteine is lower in the third trimester of pregnancy in women with enhanced folate status from continued folic acid supplementation. CLINICAL CHEMISTRY, 51 (3). pp. 629-634.

Kerr, Maeve, McNulty, Helene, Scott, J. M., Molloy, A. M., Ward, Mary, Sullivan, N., Putland, C. and Livingstone, Barbara (2005) Investigation of B vitamin status in lean and obese women: a pilot study. PROCEEDINGS OF THE NUTRITION SOCIETY, 64 (Suppl. S). pp. 39A-39A.

Woodside, JV, McMahon, R, Gallagher, Alison, Cran, GW, Boreham, CA, Murray, LJ, Strain, Sean, McNulty, Helene, Robson, PJ, Brown, KS, Whitehead, AS, Savage, M and Young, IS (2004) Total homocysteine is not a determinant of arterial pulse wave velocity in young healthy adults. ATHEROSCLEROSIS, 177 (2). pp. 337-344.

Hannon-Fletcher, Mary PA , Armstrong, Nicola, Scott , John, Pentieva, Kristina, Bradbury , Ian, Ward, Mary, Strain, Sean, Dunn, Adele, Molloy, A, Kerr, Maeve and McNulty, H (2004) Determining bioavailability of food folates in a controlled intervention study. . Americal Journal of Clinical Nutrition, 80 (4). pp. 911-918.

Hannon-Fletcher, Mary P.A , Armstrong , N, Scott , JM, Pentieva, Kristina, Bradbury, I, Ward, Mary, Strain, JJ, McCreedy, R, Alexander, J, Paterson, K, Molloy , A, Kerr (Scullion) , Maeve A and McNulty, H (2004) A controlled intervention study to compare the bioavailability of synthetic folic acid with natural food folate extracts. . Proceedings of the Nutrition Society , 63 (1(Special Issue)). pp. 41A.

McGlynn, AP, Wasson, GR, O'Reilly, S, McKelvey-Martin, Valerie, McNulty, Helene, Strain, Sean, McKerr, George, Mullan, F, Mahmud, N, Scott, J, Weir, DG and Downes, Stephen (2003) Detection of replicative integrity in small colonic biopsies using the BrdUrd comet assay. BRITISH JOURNAL OF CANCER, 88 (6). pp. 895-901.

Hunter, SJ, Boyd, AC, O'Harte, Finbarr, McKillop, Aine, Wiggam, MI, Mooney, MH, McCluskey, Janie, Lindsay, JR, Ennis, CN, Gamble, R, Sheridan, B, Barnett, CR, McNulty, Helene, Bell, PM and Flatt, Peter (2003) Demonstration of glycated insulin in human diabetic plasma and decreased biological activity assessed by euglycemic-hyperinsulinemic clamp technique in humans. DIABETES, 52 (2). pp. 492-498.

Hannon-Fletcher, Mary P.A , Armstrong, N, Scott, JM, Ward, M, Strain, JJ, Pentieva, Kristina, Dunn, Adele, Molloy, A, Kerr (Scullion), Maeve and McNulty, Helene (2003) A controlled intervention study to determine the bioavailability of food folates.. Journal of Inherited Metabolic Disease , 26 (Supp 1). pp. 11.

Hannon-Fletcher, Mary P.A , Armstrong NC, N, Scott , J, Ward, Mary, Strain, JJ, Pentieva, Kristina, Dunn, Adele, Molloy, A, Kerr (Scullion), Maeve and McNulty, Helene (2003) Bioavailability of food folates in a controlled intervention study. . Proceedings of the Nutrition Society, 62 (Supp 1). pp. 11.

O'Harte, Finbarr, Boyd, AC, McKillop, Aine, Abdel-Wahab, Yasser, McNulty, Helene, Barnett, CR, Conlon, JM, Hojrup, P and Flatt, Peter (2000) Structure, antihyperglycemic activity and cellular actions of a novel diglycated human insulin. PEPTIDES, 21 (10). pp. 1519-1526.

Boyd, AC, Abdel-Wahab, Yasser, McKillop, Aine, McNulty, Helene, Barnett, CR, O'Harte, Finbarr and Flatt, Peter (2000) Impaired ability of glycated insulin to regulate plasma glucose and stimulate glucose transport and metabolism in mouse abdominal muscle. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1523 (1). pp. 128-134.

Brattstrom, L, Landgren, F, Israelsson, B, Lindgren, A, Hultberg, B, Andersson, A, Cuskelly, G, McNulty, H, Strain, SS, McPartlin, J, Weir, DG, Scott, JM, den Heijer, M, Brouwer, IA, Blom, HJ, Bos, GMJ, Spaans, A, Rosendaal, FR, Thomas, CMG, Haak, HL, Wijermans, PW, Gerrits, WBJ, Naurath, HJ, Joosten, E, Riezler, R, Stabler, SP, Allen, RH, Lindenbaum, J, Pietrzik, K, Prinz-Langenohl, R, Dierkes, J, Saltzman, E, Mason, JB, Jacques, P, Selhub, J, Salem, D, Schaefer, E, Rosenberg, IH, Ubbink, J, van der Mere, A, Vermack, WJH, Delport, R, Becker, PJ, Potgieter, HC, Woodside, JV, Yarnell, JWG, McMaster, D, Young, IS, McCrum, EE, Patterson, SS, Gey, KF, Evans, AE, Clarke, R, Appleby, P, Harding, P, Sherliker, P, Collins, R, Frost, C and Leroy, V (1998) Lowering blood homocysteine with folic acid based supplements: meta-analysis of randomised trials. BRITISH MEDICAL JOURNAL, 316 (7135). pp. 894-898.

Boyd, AC, O'Harte, Finbarr, Gallagher, Alison, Abdel-Wahab, Yasser, McNulty, Helene, Barnett, CR and Flatt, Peter (1996) Reduced biological potency of mono-glycated insulin in vitro and in vivo in mice. DIABETOLOGIA, 39 (Suppl. 1). pp. 83.

O'Harte, Finbarr, Hunter, SJ, Boyd, AC, Wiggan, I, Ennis, CN, Gamble, R, Sheridan, B, Barnett, CR, McNulty, Helene, BELL, PM and Flatt, Peter (1995) DETERMINATION OF THE SITE OF GLYCATION OF HUMAN INSULIN AND BIOLOGICAL POTENCY USING EUGLYCEMIC CLAMPS IN MAN. DIABETOLOGIA, 38 (Suppl. 1). pp. A161.